![Rocky Mountain Discussion Group 2023 Annual Meeting](https://static.wixstatic.com/media/0ba636_054a5a60a025447d92d1efeabde5dbb5~mv2.jpg/v1/fill/w_147,h_33,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/0ba636_054a5a60a025447d92d1efeabde5dbb5~mv2.jpg)
![Rocky Mountain Discussion Group 2023 Annual Meeting](https://static.wixstatic.com/media/0ba636_054a5a60a025447d92d1efeabde5dbb5~mv2.jpg/v1/fill/w_147,h_33,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/0ba636_054a5a60a025447d92d1efeabde5dbb5~mv2.jpg)
American Association of Pharmaceutical Scientists, Rocky Mountain Discussion Group is just around the corner, and we are so excited for you to see what’s in store. We’ve brought together a unique and inspiring group of speakers, with a schedule full of engaging events and career round table session. Don’t miss out!
Program Schedule
Conference begins at 10:00 AM PDT / 11:00 AM MDT
We’re happy to share the full schedule for American Association of Pharmaceutical Scientists, Rocky Mountain Discussion Group. Check out the information below to see what’s planned and when each activity is taking place.
Introduction
11:00 AM MDT
KEYNOTE ADDRESS
Megalin/Cubilin: Role in kidney endocytosis of proteins and peptides
Mark Bryniarski, Ph.D.
Principal Scientist, Amgen
11:10 AM - 12:05 PM MDT
Microbiome-mediated effects of natural products on neurotransmitter-related molecular networks and the metabolome
Nichole Reisdorph, Ph.D.
Professor, Mass Spectrometry Core Director, University of Colorado, Skaggs School of Pharmacy and Pharmaceutical Sciences
12:05 - 12:35 PM MDT
Looking Beyond Kinact:
The Importance of Understanding The Mechanisms Behind CYP3A MBI
Larry Wienkers, Ph.D.
Principal Scientist, Weinkers Consulting, LLC
12:35 - 1:00 PM MDT
Career Round-table Group Discussion
"Academia and industry careers: breaking through the virtual wall."
TABLE: Mark Bryniarski, Ph.D., Nichole Reisdorph Ph.D., and Larry Wienkers Ph.D.
MODERATOR: Jed Lampe, Ph.D.
1:00 - 2:00 PM MDT
STUDENT/TRAINEE PRESENTATIONS
2:00-3:00 PM MDT
Inhibition of fetal CYP3A7 by HCV antiviral inhibitors
Hannah Work
Lampe Lab, University of Colorado
2:00 - 2:12 PM MDT
Drugs during pregnancy: mapping a dynamic frontier
Rachel Hudson, Ph.D.
Division of Clinical Pharmacology, University of Utah
2:12 - 2:24 PM MDT
Effect of cimetidine on metformin pharmacokinetics and endogenous metabolite levels in rats
Anoud Ailabouni
Prasad Lab, Washington State University
2:24 - 2:36 PM MDT
Manufacturing Microneedles as Novel Vaccination Strategy against Malaria
Aiden Lebya
Muttil Lab, University of New Mexico
2:36 - 2:48 PM MDT
Closing Remarks
2:48 - 3:00 PM MDT
Our Speakers
We’re proud to feature a list of prominent speakers who are at the forefront of their fields. These professionals are always eager to share their knowledge and inspire others. Don’t miss out - register today.
![Bryniarski_headshot_edited_edited.jpg](https://static.wixstatic.com/media/0ba636_6eadd33d92a7474bb9cd72db2bbfbeec~mv2.jpg/v1/fill/w_58,h_66,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/Bryniarski_headshot_edited_edited.jpg)
Mark Bryniarski, Ph.D.
Principal Scientist, Amgen
Mark obtained an MS in Pharmacology and PhD in Pharmaceutical Sciences from the University at Buffalo. After a one-year post-doctoral position in the department of Pharmaceutical Sciences at Buffalo, he was appointed as a Research Assistant Professor in the Spring of 2020. His work centered on proximal tubule protein reabsorption: the role of the protein transporter megalin (LRP2) in the renal disposition of protein therapeutics and the impact of diabetic kidney disease on megalin expression and function. In the summer of 2020, Mark joined the PKDM department at Amgen where he is currently a Principal Scientist. His primary research aim has been to characterize and quantify the target-independent clearance pathways of biologics. His work involves the development and application of novel cell-based methodologies, such as the utilization of microphysiologic systems to better define the ADME of various protein modalities.
![Larry Wienkers.jpg](https://static.wixstatic.com/media/0ba636_4ad3de6f8cbc4f119bf2954b1df7dfc5~mv2.jpg/v1/fill/w_44,h_66,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/Larry%20Wienkers.jpg)
Larry Wienkers, Ph.D.
Larry C. Wienkers received his BS in Chemistry and Biology in 1986 and his MS in Chemistry in 1988 from Western Washington University. He then went on and earned his Ph.D. in Medicinal Chemistry from University of Washington in 1993 under the direction of Dr William F. Trager. Upon graduating, he did postdoctoral work in the department of Drug Metabolism at the Upjohn Company and subsequently joined the company as a Research Scientist in 1995. In 1998 Larry became Director of Drug Metabolism Enabling Technologies at Pharmacia & Upjohn and in 2002 became Executive Director of Pharmacokinetics, Dynamics and Metabolism at Pfizer, St Louis MO. In 2004 Larry moved to Amgen to start a PKDM group in Seattle, was promoted to Vice President in 2014 and subsequently retired from his role as Global Head of the department of Pharmacokinetics and Drug Metabolism in 2018. Larry is an American Association of Pharmaceutical Scientists (AAPS) Fellow (2012); was the recipient of the University of Washington, School of Pharmacy Distinguished Alumni Award in Pharmaceutical Science and Research Award (2014) and served as Chair of American Society of Pharmacology and Experimental Therapeutics Division of Drug Metabolism (2015). In addition to consulting, he serves as an Affiliate Faculty in the Department of Medicinal Chemistry at the University of Washington and to date has published over 100 peer reviewed manuscripts and book chapters.
![Nichole Reisdorph.jpg](https://static.wixstatic.com/media/0ba636_c88ef04446794cb4a72831005c2b7b54~mv2.jpg/v1/fill/w_43,h_66,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/Nichole%20Reisdorph.jpg)
Nichole Reisdorph Ph.D.
Dr. Nichole Reisdorph is Professor in the Department of Pharmaceutical Sciences at the University of Colorado Anschutz Medical Campus and is Scientific Director of the Skaggs School of Pharmacy Mass Spectrometry Facility. As a Core Director, Dr. Reisdorph collaborates on a range of projects spanning from epilepsy and diabetes to respiratory disease and aging; giving her a broad perspective on several human diseases. The major emphasis of her own research program is on “Nutrimetabolomics”, a relatively new field that represents the intersection between nutrition studies and metabolomics. Dr. Reisdorph’s team takes a novel approach to biomarker discovery, which is based on first understanding the chemical composition of foods and plants. In addition to discovering dietary biomarkers, Dr. Reisdorph is using germ free and humanized mice to understand the role of the microbiome in metabolizing specific foods and food compounds. This research aims to understand how host:microbiome metabolism of foods and plants, such as green tea and Cannabis, affect health outcomes such as depression and anxiety. This is achieved through behavioral studies and understanding the association of food-derived metabolites with levels of neurotransmitters such as dopamine and serotonin.
Student/Trainee Speakers
![Be Wild !_edited.jpg](https://static.wixstatic.com/media/d9c0fa_cba40ad9b8b44d6c92adfbe283ff8cce~mv2.jpg/v1/fill/w_118,h_66,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/Be%20Wild%20!_edited.jpg)
Hannah Work
Lampe Lab, University of Colorado
Inhibition of fetal CYP3A7 by HCV antiviral inhibitors
![Rachel Hudson.jpg](https://static.wixstatic.com/media/0ba636_172a861aa8d34ce98effb7283b211e63~mv2.jpg/v1/fill/w_44,h_66,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/Rachel%20Hudson.jpg)
Rachel Hudson, Ph.D.
Division of Clinical Pharmacology, University of Utah
Drugs during pregnancy: mapping a dynamic frontier
![Anoud Ailabouni.jpg](https://static.wixstatic.com/media/0ba636_a2cb028c6ee74c9cb75592527e2e0763~mv2.jpg/v1/fill/w_53,h_66,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/Anoud%20Ailabouni.jpg)
Anoud Ailabouni, MS
Prasad Lab, Washington State University
Dual-Drug Antibody-Drug Conjugates for Potentiated Therapy
![Aiden Leyba.jpg](https://static.wixstatic.com/media/0ba636_a7a60bc8403442e592e6a7b89118b3f5~mv2.jpg/v1/fill/w_37,h_66,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/Aiden%20Leyba.jpg)
Aiden Leyba, MS
Muttil Lab, University of New Mexico
Next generation vaccines:
TLR7/8 agonist self-adjuvanted anti-fentanyl vaccine enhances protection from fentanyl challenge
RMDG Steering Committee
Jed Lampe, PhD
Bhagwat Prasad, PhD
Casey Sayre, PharmD, PhD
Deepa Rao, PhD
Erica Woodahl, PhD
Joseph Rower, PhD
Joe Zolnerciks, PhD
John Clarke, PhD
John Harrelson, PhD
Jonathan Constance, PhD
Kathleen Job, PhD
Venkata (Kash) Yellepeddi, PhD, RPh
Lisa Davis, PharmD
Michael Espiritu, PhD
Melanie Joy, PharmD, PhD
Pavan Muttil, PhD
Randy Adachi, PhD
Yvonne Lin, PhD
Meeting Host
Jed Lampe, PhD
Our Sponsors
We are grateful to our sponsors who have helped the RMDG to sustain scientific programming of the highest quality for the past years and many more to come!
West Pharmaceuticals
University of Montana
University of Utah, Department of Pediatrics, Clinical Pharmacology
Skaggs School of Pharmacy and Pharmaceutical Science, University of Colorado
University of New Mexico, College of Pharmacy, Department of Pharmaceutical Sciences
University of Washington
Sekisui Xenotech
Biomedical & Pharmaceutical Sciences
Daikyo
Seattle Genetics
Promega
Hertz
Solvo Biotechnology
Roseman University of Health Sciences
Nelson Laboratories
Vitro Biopharma
Activis
PharmaClean Group
Impact Analytical
WordCraft
Wasatch Scientific
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RMDG Past Meetings
Precision medicine in drug development and pharmacotherapy
August 5, 2022
Keynote Speaker: Kenneth Thummel, PhD
Seattle, WA (virtual)
Advances and Innovation in Respiratory Drug Delivery
December 10, 2021
Keynote Speaker: Heidi Mansour, PhD, RPh
Tucson, AZ (virtual)
Pharmaceutical Science in the Next Decade: Pioneering Advances in Human Health
November 13, 2020
Keynote Speaker: Hamid Ghandehari, PhD
Salt Lake City, Utah (virtual)
Exploring Biological and Mechanistic Variability in Pharmaceutical Discovery
July 26-27, 2019
Keynote Speaker: Emily Scott, PhD
Portland, Oregon
Expanding the Frontiers of Pharmaceutical Sciences
June 12-13, 2018
Seattle, Washington
Insights from the Past...Shaping the Future: Research at the Intersection of Pharmaceutics & Toxicology
September 20-22, 2017
Keynote Speakers: Anthony J. Hickey, PhD and Lois D. Lehman-McKeeman, PhD
Albuquerque, New Mexico
Addressing Health Challenges through Research in Pharmaceutical Science
August 5-6, 2016
Keynote Speaker: Leslie Benet, PhD
Las Vegas, Nevada
Pharmaceutical Sciences: From Discovery to Translation
September 23, 2015
Advancing Pharmaceutical Science to Improve Health
August 13, 2014
Missoula, Montana
Perspectives in Translational and Clinical Researchium
August 5, 2013
Salt Lake City, Utah
![green and blue medication pill_edited.jpg](https://static.wixstatic.com/media/d9c0fa_7fc2579912964df88d8168767f1d32f5~mv2.jpg/v1/fill/w_123,h_89,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/d9c0fa_7fc2579912964df88d8168767f1d32f5~mv2.jpg)